The draw for the 2012 ACN qualifiers will take place a couple of days after the final of ACN 2010, probably after February 3rd, the day of the first FIFA ranking release for 2010.
More info on the seeding and draw procedure.
With 51 members and 14 places available, CAF will probably use a system with 12 groups of 4 teams and one with 3 teams, with the winners and the best runner-up qualifying.
Pot 1: Côte d'Ivoire, Cameroon, Algeria, Ghana, Nigeria, Egypt, Burkina Faso, Tunisia, Benin, Mali, Togo, Mozambique, Zambia
Pot 2: Malawi, Morocco, Guinea, Kenya, Rwanda, Sudan, Uganda, South Africa, Senegal, Cape Verde Islands, Congo, Angola, Tanzania
Pot 3: Namibia, Congo DR, Gambia, Zimbabwe, Libya, Botswana, Ethiopia, Sierra Leone, Swaziland, Chad, Burundi, Lesotho, Madagascar
Pot 4: Liberia, Mauritania, Eritrea, Niger, Seychelles, Comoros, Mauritius, Somalia, Djibouti, Guinea-Bissau, Central African Republic, Sao Tome e Principe
I think there won't be any friendly matches during Angola 2010, so the last two pots are pretty much set in stone. Only Gambia can improve their position if they don't lose against Tunisia tomorrow.
Group 1: Côte d'Ivoire, Tanzania, Madagascar, Sao Tome e Principe
Group 2: Cameroon, Angola, Lesotho, Central African Republic
Group 3: Algeria, Congo, Burundi, Guinea-Bissau
Group 4: Ghana, Cape Verde Islands, Chad, Djibouti
Group 5: Nigeria, Senegal, Swaziland, Somalia
Group 6: Egypt, South Africa, Sierra Leone, Mauritius
Group 7: Burkina Faso, Uganda, Ethiopia, Comoros
Group 8: Tunisia, Sudan, Botswana, Seychelles
Group 9: Benin, Rwanda, Libya, Niger
Group 10: Mali, Kenya, Zimbabwe, Eritrea
Group 11: Togo, Guinea, Gambia, Mauritania
Group 12: Mozambique, Morocco, Congo DR, Liberia
Group 13: Zambia, Malawi, Namibia